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Physical trauma or something in the environment — such as a viral or bacterial infection — may trigger psoriatic arthritis in people with an inherited tendency.

Over time, it can lead to joint damage and can also impact quality of life.

Depression and anxiety can stem from the mental burden of living with a chronic disease, and a growing body of research suggests that skin involvement as well as inflammation from arthritis can raise the risk of anxiety and depression in people with PsA specifically.

A study published in the found that the prevalence of both anxiety and depression was higher in patients with PsA than those with psoriasis without psoriatic arthritis, for instance, and was associated with higher actively inflamed joint count as well as disability, pain, and fatigue.

show that higher numbers or activity of these T cells and the cytokines they release are linked to PsA symptoms and severity.

Other Environmental Factors Other health and environmental factors can of PsA, including:• New England Journal of Medicine.

Examples include the Achilles tendon, the plantar fascia, and the tendon sheath in the hand.

Be sure to choose fragrance-free laundry and skin care products, which are less likely to lead to skin irritation.

Philadelphia, PA: Elsevier; 2019:chap 131.

Your provider may suggest a mix of rest and exercise.